Smoking is the main cause of emphysema

What is the cause of emphysema? Smoking is the main cause of emphysema, accounting for more than 80 percent of all cases. most common in people over 40 who have smoked for many years. Prolonged exposure to tobacco smoke may also play a role. Smoking emphasizes the natural antioxidant defense system of the lungs, allowing free radicals, tissue damage until the cellular level. When lasix prescription tobacco smoke is inhaled, from 80 to 90 percent remains in the lungs and causes

irritation, increased mucus production and damage to the deep parts of the lungs. After mucus and tar clogged air tubes that lead to chronic bronchitis and emphysema. People who lack the protein alpha-1 antitrypsin (AAT) have a higher risk of developing severe. Alpha-1 antitrypsin (AAT deficiency) is a hereditary disease and occurs in varying degrees. Deficiency leads to A1AD related emphysema when the liver produces insufficient AAT to control the natural enzyme known as neutrophil elastase. Although neutrophilic elastase plays an important role in fighting bacteria and cleaning of dead tissue lung, it ultimately leads to irreversible damage to the alveoli, damaging and destroying their elastic fibers, if there is enough AAT for its neutralization. For individuals with AAT deficiency who smoke, the risk of developing emphysema is much greater than for the general population. A1AD related emphysema usually strikes people in their thirty-forty years old and very rare in children. Among other causes of emphysema are industrial pollutants, aerosols, no smoke, combustion engine exhaust gases and physiological atrophy associated with age (senile emphysema). Physical injury in an accident and then scarring can lead to scar emphysema, severe respiratory efforts can rupture alveoli in cases of near suffocation, whooping cough, work (childbearing), and acute pneumonia. Tuberculosis and asthma can also lead to a slight tension, seriously damaging the elastic fibers and alveolar wall involvement in emphysema. High altitude is associated with higher mortality among COPD suffer, but not proven a causal factor at this time. Areas of high poverty also experience a higher mortality rate among people with chronic obstructive airway disease may reflect lack of medical care. .